Incorrect classification of low bone mass, as ...

Go to the publisher. In a study of Bowden et al

vitamin D status reported 85 children, aimed at the pediatric clinic of metabolic bone. The authors concluded that vitamin D

total failure, even in children with recognized osteopenia and osteoporosis caused by primary metabolic bone disease

or secondary to chronic diseases. While interesting and provocative, several methodological flaws causing concern

validity of its findings and conclusions. One major problem is their use in the osteopenia and osteoporosis. Despite the recognition by the authors

no consensus criteria based on bone mineral density (IPC) for osteopenia or osteoporosis in children, they randomly

use IPC lumbar spine

g points from 1 . 0 and 2. 0 defines osteopenia and less than 2. 0 defines osteoporosis. ABOUT

d score of 1. 0 and 2. 0 is considered within normal limits for children. Determining that they use against

Published International Society for Clinical densitometry,

is recommended to use the terms low bone density for chronological age and below the expected range for age, if al the expense of less than 2. Is 0. We are also concerned that went wrong in correcting the source data to create ABOUT d points. For children with delayed linear growth and / or maturation, the International Society for Clinical densitometry has

recommended adjustment range ABOUT absolute height or height age, or comparing ON in pediatric reference data that provide

age-sex - and height concrete

d points. Although the authors did adjust for weight ABOUT sex and status, they do not adjust in height, which is likely

incorrectly classified the number of children. Incorrect classification of low bone mass as a result of misinterpretation dual energy X-ray

absorbtsiometrii results or incorrect use of reference data, as reported in the pediatric population. ,

Recent data do not allow to draw conclusions about the relationship between the IPC and low vitamin D status, as

all children referred to the bone clinic were included in the study, not only lasix heart medication with low defense. In addition, as

no control group and hypovitaminosis D is often in healthy children

conclusion that 80% of subjects were 25-hydroksyvytamyna D concentrations 30 ng / ml tells us about the relationship between minimum

vitamin D status and low defense. Although Bowden et al study showed that hypovitaminosis D was common in children called metabolic bone clinic,

one can not draw conclusions about the relationship between the level of vitamin D, low IPC and children's bone disease. This conclusion

research needs with the appropriate control group, even the population of the subject, and accurate determination of low

ABOUT. We appreciate the authors draw attention to this subject, however, we urge readers to evaluate their results with caution

subject to the limitations discussed above. .