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Kenneth Todor, Ph.D.
much noise made about microbial diversity. Unicellular eukaryotes
(protystov) have sufficient structural diversity, but
prokaryotes (bacteria and archaea) there is no difference. There
only a few basic morphology, and mobility features
resting cells (spores) and the main differential stain (Gram) >> << that distinguishes prokaryotes under the microscope. Yes
, what all the hype about about prokaryotes? It is about
biochemical or metabolic diversity
especially with regard to energy generating metabolism and biosynthesis of secondary buy generic lasix metabolites
. Prokaryotes, as a group, spend more
the same types of basal metabolism, as eukaryotes, but also is
several types of energy generating metabolism among prokaryotes
that is nonexistent in eukaryotic cells or organisms. Diversity
prokaryotes express their great differences in the ways of energy production and
metabolism, and this feature allows prokaryotes to flourish in all habitats
suited for life on Earth. Even prokaryotic species may be more flexibility in metabolism >>. Consider
<< Escherichia coli. This bacterium can
food energy for growth by fermentation or respiration. He can breathe
aerobic O
use as a final acceptor of electrons, or it can breathe on
anaerobically without
or fumarate as terminal electron acceptor
. E. coli
can use glucose or lactose as the sole carbon source
growth, and metabolic ability to convert sugar into all >> << essential amino acids, vitamins and nucleotides that make up the cells. A relative of Escherichia coli
,
Rhodospirillum hihit,
has all heterotrophic capabilities as E. coli, plus
able to grow on
zfotoavtotrofnoyi, photoheterotrophic or litotrofnyy funds. It does require a >> << growth factor, however, biotin should be added to its nutrient environment. In fact, most eukaryotic energy production (ATP) with alcohol
fermentation (eg yeast), lactic fermentation (eg, muscle cells, neutrophils
), aerobic respiration (eg, shapes, simple animals ) or
oxygen photosynthesis (eg, algae, plants). These modes of energy-generating metabolism
exist among prokaryotes, in addition to all these types of energy
production, which practically do not exist in eukaryotes. Unique fermentation fermentation Other ways anaerobic respiration Lithotrophy Photoheterotrophy beskyslorodnoho photosynthesis methanogenesis light-driven nonphotosynthetic fotofosforyluvannya also among autotrophic prokaryotes, there are three ways
CO fixes, two of which are unknown among eukaryotes,
CODH
(acetyl CoA) and reverse CTC. The term metabolism refers to the amount of biochemical reactions
necessary for energy production and energy to synthesize
cellular material with small molecules in the environment. Thus, metabolism is
generating component, called
catabolism, and energy-intensive
,
biosynthetic component called
anabolism. Catabolic reactions or sequences of energy production, as
ATP, which can
be used in anabolic reactions at a cellular material with
nutrients in the environment. The relationship between catabolism and anabolism
shown in Figure 1 below. Figure 1.
Relations between catabolism and anabolism in the cell. During catabolism, energy
changed from one form to another, and in accordance with the laws of thermodynamics,
such energy conversion never fully effective, i. ie, some amount of energy
lost as heat. The effectiveness of catabolic
sequence of reactions is the amount of energy allocated to the cell (for
anabolism)
divided by the total amount of energy released during the reaction. During catabolism, useful energy is temporarily stored in >> << "
high binding energy»
ATP -
adenosine triphosphate. No matter what
form of energy cells use as their primary energy source is ultimately converted
and stored as ATP - the universal currency of energy metabolism in
biological systems. Once the energy during anabolism, it can be spent as
high energy of ATP, which has a value of about 8 kcal mol at. Thus,
converting ADP into ATP requires 8 kcal of energy, and
hydrolysis of ATP to ADP releases 8 kcal. Figure 2. Structure
ATP. ATP is derived from the nucleotide adenozynmonofosfatu (AMP) or adenylic acid
in which two additional phosphate groups are connected through pyrophosphate
bonds (~ P). These two energy-rich bonds in the sense that th
hydrolysis gives much more power than the corresponding covalent bond. ATP
acts as a coenzyme in the energy response relationship where one or both groups
terminal phosphate is removed from the ATP molecule with
binding energy used for transmission of AT >> << other molecules
intensify its role in metabolism. For example, Glucose + ATP
Glucose-P
ADP or amino acids + ATP ----- AMP-Amino
acid + PP. Due to the central role of ATP in the energy generating metabolic
expect to see their participation as a coenzyme in most produce energy
processes in cells. Kenneth Todor, Ph.D. All rights reserved. - WWW. textbookofbacteriology. Net >>. <<
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